Figure 2.

CBD-X downregulates the secretion of pro-inflammatory cytokines from human neutrophils. Isolated neutrophils were treated with 2 µg/mL CBD-X. Treated cells were activated via 100 ng/mL LPS overnight. Levels of IL-8 and IL-6 (a,b) were detected via ELISA. Each colored dot represents one donor. The means were calculated from healthy donors (black big dot) and each dot represents one case. Data were analyzed via one-way ANOVA (Fisher’s LSD test with values p < 0.05 considered statistically significant, (** p < 0.01, *** p < 0.001).