Table 3.

DOE matrix with nominal values of the experimental factors and the response (Y), which was calculated as $t_0-t_1$. Replicates were performed at the center and vertices of the cube.

Sample	Q	T (min)	T	Y
C1	0.5	32	15	0.207
C1bis	0.5	32	15	0.228
C2	0.5	32	35	0.204
C2bis	0.5	32	35	0.224
C3	0.5	92	15	0.144
C3bis	0.5	92	15	0.126
C4	0.5	92	35	0.090
C5	0.5	62	25	0.213
C6	2.5	32	35	0.495
C6bis	2.5	32	35	0.470
C7	2.5	32	15	0.517
C8	2.5	32	15	0.517
C9	2.5	92	15	0.465
C9bis	2.5	92	15	0.456
C10	2.5	92	35	0.350
C11	2.5	62	25	0.501
C12	1.5	62	25	0.389
C12bis	1.5	62	25	0.403
C14	1.5	62	35	0.377
C15	1.5	62	15	0.407
C16	1.5	92	25	0.329
C17	1.5	32	25	0.470