Figure 3.
Sequence identity and Antigenic Site Characterization. All of the HA sequences used in the studies were aligned and analyzed for sequence identity and similarity scores and shown using a Gonnet similarity matrix. The H1-HA amino acid sequences were aligned using ClustalW, and the variable head domains and antigenic sites are indicated by the boxes (A). The H3-HA amino acid sequences were aligned using ClustalW, and the variable head domains and antigenic sites are indicated by the boxes (B). The similarity matrices and alignments were performed using MacVector (version 18.6.4). The (Sa, Sb, Ca, and Cb) of the H1 and (A, B, C, D, and E) antigenic sites of the H3 HA proteins are indicated by the boxed regions.