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. 2024 Oct 10;16(10):1316. doi: 10.3390/pharmaceutics16101316

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of MSCs-derived EVs on wound healing and cell proliferation in vitro. (A) Representative optical images of wound healing in HPAEpiC monolayer. Magnification: 20×. Scale bar: 50 µm. Percentage of wound closure in HPAEpiC 24 h after being treated with C-EVs and LPS-EVs. (B) Percentage of cell viability of HPAEpiC 24 h after being treated with C-EVs and LPS-EVs, considering that non-treated cells (control) had 100% cellular viability. Data are presented as mean ± SEM of eight (A) and four (B) independent experiments with two replicates of each condition; * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001. Abbreviations: extracellular vesicles, EVs.