TABLE 2.

CD4⁺-T-cell epitopes identified in EBNA3C^a

EBNA3C aa	Epitope sequence	No. of responders	Potential restrictionb
			DR	DQ
66–80	NRGWMQRIRRRRRRR	2	1, 13	5, 6
141–155	ILCFVMAARQRLQDI	1	1, 13	5, 6
386–400	SDDELPYIDPNMEPV	6	1
401–415	QQRPVMFVSRVPAKK	1	11, 14	3, 5
546–560	QKRAAPPTVSPSDTG	1	1, 13	5, 6
586–600	PPAAGPPAAGPRILA	1	1, 13	5, 6
626–640	PPVVRMFMRERQLPQ	1	11, 14	3, 5
649–660	PQCFWEMRAGREITQ	2	None	None
916–930	PSMPFASDYSQGAFT	3	4
961–986	AQEILSDNSEISVFPK	4	[4]	[2, 3, 5]

^aThe sequence of EBNA3C is derived from the B95.8 prototype strain of EBV. 

^bPotential restriction elements were identified as described for Table 1. None, responders had no shared DR or DQ allele.