TABLE 3.

CD4⁺-T-cell epitopes identified in LMP1 and LMP2^a

Antigen and aa	Epitope sequence	No. of responders	Potential restrictionb
			DR	DQ
LMP1
130–144	LWRLGATIWQLLAFF	1	1, 4	1, 3
212–226	SGHESDSNSNEGRHH	3		2
340–354	TDGGGGHSHDSGHGG	1	NDc	ND
LMP2
149–163	STVVTATGLALSLLL	2	1, 13	5
169–182	SSYAAAQRKLLTPV	2	1, 13	5, 6
224–243	VLVMLVLLILAYRRRWRRLT	2	None	None
385–398	STEFIPNLFCMLLL	1	ND	ND

^aThe sequences of LMP1 and LMP2 are derived from the B95.8 prototype strain of EBV. 

^bPotential restriction elements were identified as described for Table 1. 

^cND, not determined.