Table 4.

Overdose deaths.

First Author, Year, Country	Population Studied	Effect Size	95% Confidence Interval	Other Outcomes
Abrahamsson, 2017, Sweden [18]	OAT population (n = 4501)	Not significant HR 1.4, (90 day exposure)	0.97–2.29	Increased non-overdose cause of death (HR 2.02, 95% CI 1.29–3.18). Sensitivity analysis of 30 days exposure was significant.
MacLeod, 2019, UK [24]	Primary care OAT, England (n = 12,118)	Increased HR 3.34	2.14–5.20	Multiple other analyses. Retention increased.
Park, 2020, USA [28]	Buprenorphine OAT (n = 63,345)	Increased HR 2.92	2.10–4.06	Retention increased.