Table 3.
Articles | Autoantibodies | PFT | Laboratory Investigations |
Correlating NVC Variables with Other Features |
---|---|---|---|---|
Microvascular capillaroscopic abnormalities and occurrence of antinuclear autoantibodies in patients with sarcoidosis.
[45] |
Blood tests for ANA and ENA. PRP patients were, for definition, all negative for ANA and ENA tests. In the prevalence of ANA positivity in SA patients were significantly higher in comparison with PRP patients (p = 0.001) and HCs (p = 0.015). |
SA patients underwent PFTs (including plethysmography) to measure percent predicted forced vital capacity (FVC%), forced expiratory volume in 1 s (FEV1%), diffusing capacity of carbon monoxide (DLCO%) and total lung capacity (TLC%). | (WBC), (Hb), (PLT) (CRP), (25OH-D), (Ca) and (ACE) concentrations, the latter two being considered most correlating with sarcoidosis disease activity. Blood samples collected, at most, 3 months before NVC examination. | Negative correlation between capillary dilations and serum ACE concentrations and between the mean capillary number and CRP serum concentrations, positive correlation between mean absolute capillary count and the FVC%. |
Microvascular damage evaluation based on nailfold video-capillaroscopy in sarcoidosis.
[46] |
All patients with a diagnosis of sarcoidosis included in the study had negative ANA test results. | FEV1, forced vital capacity (FVC), and diffusion capacity for carbon monoxide (DLCO)] were measured at admission. | The acute phase reactants (ESR and CRP), antinuclear antibody (ANA), hematological (white blood cells, haemoglobin, and thrombocyte), and biochemical test results (creatinine, calcium, albumin, glucose, and uric acid) at the last visit of sarcoidosis patients were obtained from the hospital database. | No significant correlation was found between the laboratory results, CT stage, treatments, disease duration (chronic-acute disease), and capillaroscopy findings of the patients with SA. In patients with SA, the FEV1 value was lower in patients with a crossing rate > 50% than in those with a crossing ratio below 50%. |
Legend. (PRP) primary Raynaud’s phenomenon.