TABLE 4.

Association of homozygosity at HLA class I loci with CD8⁺ CTL response to ALVAC-HIV canarypox vaccine^a

Locusb	HIV proteinc	No. (%) of persons at 2 wks after 3rd or 4th dose (wk 26)		ORd
		Homozygous	Heterozygous
HLA-A	Any	3 (9)	31 (13)	0.7
	Gag	3 (16)	16 (15)	1.3
	Env	2 (10)	18 (17)	1.2
HLA-B	Any	3 (12)	22 (10)	1.1
	Gag	3 (18)	14 (13)	1.6
	Env	1 (6)	16 (14)	0.6

^aEffect on natural history as described in references 8, 29, and 50. 

^bSee text for typing details; a total of 273 and 285 were unambiguously typed to the four-digit level at the A and B loci, respectively. 

^cVaccine-specific viral protein against which CTL response was measured. 

^dAll P values were >0.15.