Table 4.
| General |
| Fatigue |
| Malaise |
| Sleep problems |
| Chronic pain |
| Psychiatric |
| Depression |
| Anxiety |
| Post-traumatic stress disorder |
| Dysthymia |
| Cutaneous |
| Dyspigmentation |
| Pruritus |
| Photosensitivity |
| Abnormal sweating |
| Eruptive nevi |
| Cutaneous scars |
| Postinflammatory skin changes |
| Nail loss |
| Hair loss |
| Ocular |
| Dry eyes |
| Symblepharon |
| Eyelid dysfunction |
| Chronic ocular surface inflammation |
| Opacification |
| Conjunctivalization |
| Keratinization |
| Neovascularization |
| Punctal damage and tear duct scarring |
| Pain |
| Photophobia |
| Visual impairment (i.e., loss of acuity) |
| Oral mucous membrane |
| Dryness |
| Dental caries |
| Abnormal root development |
| Hypoplasia of permanent teeth |
| Ulceration and synechiae |
| Mucosal scarring |
| Permanent loss of tongue papillae/dysgeusia |
| Dysosmia |
| Otorhinolaryngologic |
| Hypopharyngeal stenosis and impaired swallowing |
| Pharyngeal-bronchial fistula formation and recurrent aspiration |
| Dysphonia |
| Otalgia |
| Tinnitus |
| External auditory canal stenosis |
| Nasal septal synechiae |
| Pulmonary |
| Dyspnea |
| Cough |
| Wheezing |
| Obstructive lung disease (i.e., bronchiolitis obliterans, bronchiectasis, chronic obliterative bronchitis) |
| Gastrointestinal |
| Esophageal stricture or webs |
| Dysphagia |
| Intestinal ulcers |
| Malabsorption (secondary to duodenal villi destruction) |
| Diarrhea |
| Gynecologic/Genitourinary |
| Vulvar pain/dyspareunia |
| Vulvar and vaginal adenosis or stenosis |
| Labial fusion |
| Hematocolpos and hydrocolpos (secondary to complete vaginal fusion) |
| Subfertility or infertility (secondary to menstrual abnormalities) |
| Urethral erosions and strictures |
| Balanitis |
| Phimosis |
Of note, studies have reported that hepatic and renal complications are thought to be the result of drug hepatotoxicity and nephrotoxicity rather than a direct result of SJS/TEN disease state, so these were excluded from our table