Table 3.
Univariate Cox Regression analysis for cancer specific survival in patients with penile cancer.
| Characteristics | HR | 95%-CI | p-Value |
|---|---|---|---|
| Age at diagnosis | 1.07 | 0.997–1.15 | 0.061 |
| Presence of sarcopenia (SMI) | 2.21 | 0.52–9.28 | 0.278 |
| Presence of sarcopenia (PMI) | 7 | 0.86–57.09 | 0.069 |
| SMI (continous) | 0.95 | 0.88–1.03 | 0.220 |
| PMI (continous) | 0.57 | 0.34–0.96 | 0.037 |
| VSR (continous) | 1.23 | 0.31–4.91 | 0.773 |
| High VSR | 1.48 | 0.35–6.19 | 0.593 |
| VFI | 0.99 | 0.97–1.01 | 0.443 |
| SFI | 0.98 | 0.96-1.0 | 0.249 |
| VO | 0.67 | 0.16–2.82 | 0.589 |
| pT-stage | |||
| pTis | 0.04 | 0.00-453.3 | 0.500 |
| pT1 | 0.95 | 0.23–3.98 | 0.945 |
| pT2 | 0.88 | 0.18–4.36 | 0.875 |
| pT3 | 2.16 | 0.51 − 0.06 | 0.293 |
| pN-stage | 125.39 | 0.29-53405.57 | 0.118 |
| cM-stage | 11.47 | 2.53–52.05 | 0.002 |
| BMI | 1.1 | 0.94–1.27 | 0.228 |
| BMI cat. | |||
| Normal | 0.76 | 0.15–3.79 | 0.742 |
| Overweight | 0.50 | 0.10–2.49 | 0.399 |
| Obese | 2.37 | 0.59–9.47 | 0.224 |
| Phimosis | 2.06 | 0.49–8.46 | 0.324 |
| ASA-Score | |||
| 1 | 1.59 | 0.32–7.86 | 0.573 |
| 2 | 0.32 | 0.06–1.57 | 0.148 |
| 3 | 2.20 | 0.55–8.83 | 0.266 |
| Smoker | 1.11 | 0.26–4.63 | 0.891 |
| Localization | |||
| Foreskin | 0.05 | 0.00-13975.82 | 0.631 |
| Glans | 0.53 | 0.13–2.11 | 0.365 |
| Shaft | 3.4 | 0.80-14.37 | 0.096 |
| Multilocular | 0.95 | 0.12–7.72 | 0.961 |
| DM | 1.51 | 0.30–7.47 | 0.617 |
| Private insurance | 0.742 | 0.15–3.68 | 0.715 |
| Alcohol abuse | 0.99 | 0.12–8.11 | 0.996 |
| Creatinine | 1.106 | 0.26–4.63 | 0.891 |
| Chemotherapy | 2.70 | 0.64–11.35 | 0.201 |
| CCI | |||
| 0 | 1.14 | 0.14–9.32 | 0.900 |
| 1–2 | 0.26 | 0.03–2.13 | 0.211 |
| 3–4 | 3.29 | 0.79–13.78 | 0.103 |
| ≥ 5 | 0.57 | 0.07–4.65 | 0.600 |
| LND | |||
| None | 0.66 | 0.13–3.28 | 0.613 |
| Modified | 0.34 | 0.04–2.78 | 0.315 |
| Radical | 0.04 | 0.00-453.31 | 0.501 |
| Pelvin | 5.02 | 1.2-21.07 | 0.027 |
HR, hazard ratio; CI, confidence interval; SMI, skeletal muscle index; PMI, psoas muscle index; VSR, visceral-to-subcutaneous fat ratio; VFI, visceral fat index; SFI, subcutaneous fat index; VO, visceral obesity; pT-stage, pathological Tumor stage; pN-stage, pathological nodal classification; cM-stage, clinical metastases classification; BMI, body mass index; ASA, American Society of Anesthesiologists. CCI, Charlson comorbidity index; LND, lymph node dissection; p < 0.05 is considered statistically significant.