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ROC analysis to assess the diagnostic performance of the five markers in discriminating patients with HAM from HTLV-1 carriers. We collected the past data of five known markers, the PVL in PBMCs, the PVL in CSF cells, the ratio of these PVLs, CSF CXCL10, and CSF neopterin, in 92 individuals (69 patients with HAM and 23 HTLV-1 carriers). PVL, HTLV-1 proviral load; PBMCs, peripheral blood mononuclear cells; AUC, area under the curve.
