Lesion	Score
	0 (Normal)	1 (Minimal)	2 (Mild)	3 (Moderate)	4 (Marked)
Skeletal muscle
Skeletal myocyte degeneration/necrosis ± inflammatory cell infiltration, mainly neutrophils.	None	Occasional, scattered single or small groups of degenerating myocytes—up to 5% of skeletal muscle affected.	Increased numbers of degenerating myocytes—6–25% of skeletal muscle affected.	Frequent numbers of degenerating myocytes—26–50% of skeletal muscle affected.	Numerous degenerating myocytes—>50% of skeletal muscle affected.
Skin and subcutis
Vascular congestion, oedema and haemorrhage with a mixed inflammatory cell infiltrate, often predominantly neutrophils, with fewer macrophages and lymphocytes.	None	Up to 5% of skin and soft connective tissues affected.	6–25% of skin and connective tissues affected.	26–50% of skin and connective tissues affected.	>50% of skin and connective tissues affected.