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. 2024 Oct 15;16(10):1615. doi: 10.3390/v16101615

Figure 2.

Figure 2

Circulating concentrations of inflammatory and endothelial markers at presentation in patients with COVID-19 by mortality outcome at D28: GeoSentinel (2020–2021). Circulating concentrations of inflammatory and endothelial markers at inclusion including (A) IL-6, (B) VWF-a2, (C) C5a, (D) IL-1Ra, (E) Il-8, (F) sTREM-1, and (G) suPAR stratified by mortality outcome at D28. Survived includes those who were discharged home (n = 141), discharged to hospice/long-term care (n = 4), or were in hospital (n = 19) at D28. Deaths include those who died before 7 days (n = 4) and deaths between 7 and 28 days (n = 12). Concentrations of C5a (C) have been logged for visualization. Significant p-values (p < 0.05 by Wilcoxon rank sum test) are in bold. Abbreviations: complement component C5a (C5a), interleukin-1 receptor antagonist (IL-1Ra), interleukin-6 (IL-6), interleukin-8 (IL-8), soluble tumor necrosis factor receptor-1 (sTREM-1), soluble urokinase-type plasminogen activator receptor (suPAR), von Willebrand factor (VWF-a2).