Table 4.
Commonly used HTLV-1 cell lines.
| Cell Line | Cell Type | IL-2 Dependency | Antigen Expression | |
|---|---|---|---|---|
| HTLV-1-transformed cell lines | MJ [103] | Lymphoblast | Independent | CD2+; CD3+; CD4+ |
| MT-2 [104] | Lymphoblast | Independent | CD4+; CD25+; FoxP3+ | |
| MT-4 [105] | Lymphoblast | Independent | CD4+ | |
| HuT-102 [1] | Cutaneous T Lymphocyte | Dependent | CD4+ | |
| C81-66 [106] | Lymphoblast | Independent | CD4+ | |
| HTLV-1 chronically infected cell lines | C91/PL [103,107] | Umbilical cord-blood T cells | Independent | CD4+ |
| MS-9 [108] | Cord-blood T cells | Dependent | CD4+ | |
| ATL cell lines | MT-1 [109] | Lymphoblast | Independent | CD4+; Tax− |
| MT-3 [110] | Lymphoblast | Independent | CD4+; Tax− | |
| ATL-2 [111] | Lymphoblast | Independent | CD4+; CD3− | |
| TL-Om1 [112] | Lymphoblast | Independent | CD4+; Tax− | |
| F6T [113] | Lymphoblast | Independent | CD4+; CD25+ | |
| K3T [113] | Lymphoblast | Independent | CD4+; CD25+ | |
| S1T [113] | Lymphoblast | Independent | CD4+; CD25+ | |
| ATL-T [114] | Lymphoblast | Independent | CD4+ | |
| ATL-35T [115] | Lymphoblast | Independent | CD4+ | |
| ATL-55T [116] | Lymphoblast | Dependent | CD4+ | |
| Su9T01 [113] | Lymphoblast | Independent | CD4+ |