Figure 5.

Overview of acetylation levels across the KEGG pathways — involved in cellular processes, environmental information processing, genetic information processing and human diseases - in P. aeruginosa. The colour of each cell in the heatmap corresponds to fraction of genes involved in a KEGG pathway for which their corresponding proteins were found to be acetylated. This fraction is also referred to as the acetylation level of a pathway in this paper. Specifically, two acetylomes from P. aeruginosa strain PA14 were compared with our PAO1 acetylome (Ouidir et al. 2015, Gaviard et al. 2018). Transcription-related genes were highly acetylated in all three datasets (e.g. TCA cycle). For some pathways differences could be seen (e.g. ribosome). However, no clear separation of the acetylomes based on the strain to which they belong, could be seen.