Table 1.
Model Inputs and Parameters
| Model Parameters | Inputs | |
|---|---|---|
| Time-Horizon | 1 Year | |
| Number of Patients | 10,000 | |
| Percent Adherent at Baseline | 37.1% | |
| Increase in Patients Adherent due to Blister-Packaging | 13% | |
| Relapse-specific HCRU: | Adherent | Non-Adherent |
| OUD-HCRU | ||
| Continuous episodic dependence | 2.7% | 1.9% |
| Inpatient admission, primary diagnosis OUD | 3.8% | 15.9% |
| Detox, any diagnosis opioid use | 4.8% | 15.9% |
| ED visit, any diagnosis opioid use | 3.6% | 9.7% |
| Composite relapse | 11.4% | 26.3% |
| All-Cause HCRU | ||
| Inpatient admission | 17.9% | 40.1% |
| ED visit | 10.0% | 51.9% |
| Mean outpatient office visits | 13.2 | 10.0 |
| Mean Rx Claims | 42.3 | 35.3 |
| All-Cause Healthcare Costs | ||
| Inpatient Costs | $3025 | $11,741 |
| Outpatient Costs | $10,697 | $16,828 |
| --ED Costs | $713 | $1,703 |
| --Outpatient office visit costs | $1783 | $1423 |
| --Other Outpatient costs | $8202 | $13,703 |
| *Medical Costs | $13,724 | $28,569 |
| Pharmacy Costs | $9446 | $5248 |
| Total Healthcare Costs | $23,351 | $33,819 |
Notes: --Included in outpatient costs (ED costs, outpatient office visit costs, other outpatient costs). *Medical costs include both inpatient costs and outpatient costs.
Abbreviations: ED, emergency department; HCRU, healthcare resource utilization; OUD, opioid use disorder; Rx, prescription.