Table 3.

Sensitivity Analysis Results

	Base Case Difference Post-Pre		Lower Bounds Difference Post-Pre		Upper Bounds Difference Post-Pre
	Aggregate	Percent/ Mean	Aggregate	Percent/ Mean	Aggregate	Percent/ Mean
Number of patients adherent	818	8.2 percentage points	883	8.8 percentage points	671	6.7 percentage points
Relapse-Specific Healthcare Resource Utilization
Continuous episodic dependence	7	0.1%	3	<0.1%	11	0.1%
Inpatient admission, primary diagnosis OUD	−99	−1.0%	−87	−0.8%	−105	−1.0%
Detox, any diagnosis opioid use	−91	−0.9%	124	1.2%	−99	−1.0%
ED visit, any diagnosis opioid use	−50	−0.5%	−46	−0.4%	−56	−0.6%
Composite relapse	−122	−1.2%	−103	−1.0%	−141	−1.4%
All-Cause Healthcare Resource Utilization
Inpatient admission	−182	−1.8%	−153	−1.6%	−207	−2.1%
ED visit	−601	−6.0%	−866	−8.6%	−566	−5.7%
All-Cause Healthcare Costs
Inpatient Costs	-$7,127,073	-$713	-$5,617,599	-$562	-$7,621,782	-$762
Outpatient Costs	-$5,013,319	-$501	-$4,988,788	-$499	-$7,000,330	-$700
Pharmacy Costs	$3,432,705	$343	$3,090,088	$309	$4,977,340	$498
Total Healthcare Costs	-$8,559,684	-$856	-$4,977,340	-$498	-$11,585,174	-$1159

Abbreviations: ED, emergency department; OUD, opioid use disorder.