Table 4. Haplotype analysis of the MTHFR C677T and A1298C polymorphisms in the study population.
| Haplotypes | Control (n = 544) n (%) | T2DM (n = 890) n (%) | OR (95% CI) | P-value |
|---|---|---|---|---|
| C-A | 260 (47.79) | 363 (40.79) | 1.000 (reference) | – |
| T-A | 185 (34.01) | 337 (37.87) | 1.305 (1.027–1.658) | 0.030* |
| C-C | 97 (17.83) | 171 (19.21) | 1.263 (0.939–1.697) | 0.122 |
Notes.
- OR
- adds ratios
- 95% CI
- 95% confidence interval
P < 0.05