Fig. 5. Gene communities in H. influenzae and M. catarrhalis infections during exacerbation and their associated biological functions.

In this heatmap, columns represent gene communities from acute exacerbation events presenting H. influenzae (EXHI label) and M. catarrhalis (EXMC) infections, and the rows represent associated biological functions (annotated in blood transcription modules, microRNA targets, transcription factor targets and Hallmark biological functions). Each cell of the heatmap is colored proportionally to the average Benjamini-Hochberg corrected log₁₀ p value, testing the enrichment of the ith biological function in the jth gene community. AECOPD acute exacerbations of COPD; COPD chronic obstructive pulmonary disease.