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. 2024 Oct 26;14:25589. doi: 10.1038/s41598-024-76268-2

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 6 — Observed rescue effects in C. elegans MT knock-in strains. MT knock-in strains (10md-MT and 2d-MT) referred to the N2 wild-type or the MT-deficient mtl-1 strain under control (no Cd²⁺ exposure) or Cd²⁺ exposure conditions. (A) Colors denote that observed effects are either not significant (grey) (p > 0.05 at 95% confidence), close to significance indicating a biological trend (light green) (p > 0.07), or significant (dark green) (p < 0.05 at 95% confidence). (B) Data of panel A is reduced to indicate the observed rescues effect of the two MT strains, compared to both reference strains (N2, mtl-1): ‘-‘ no rescue effect, ‘~’ partial rescue effect, ‘+’ rescue effect, ‘++’ outperformance.