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. Author manuscript; available in PMC: 2024 Oct 27.
Published in final edited form as: Semin Cell Dev Biol. 2022 May 6;138:36–44. doi: 10.1016/j.semcdb.2022.04.008

Figure 1. In vivo cellular potential and shared gene regulatory circuitry of blastula and neural crest stem cells.

Figure 1.

Top panels illustrate the in vivo potential of blastula stem cells (ectoderm, mesoderm, and endoderm) and neural crest cells (ectodermal: pigmentation, peripheral glia, sensory neurons and mesenchymal: connective tissue, cartilage/bone, dermis). Bottom panels show common gene regulatorys circuitry for blastula stem cells and neural crest factors. Circuity is grouped in boxes by shared (blue), ESC-specific (orange), and neural crest-specific (green) gene regulatory elements.