Comparison 1. Endothelin receptor antagonist versus placebo.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 DIND	3	1976	Risk Ratio (M‐H, Fixed, 95% CI)	0.80 [0.67, 0.95]
2 Mortality	4	2010	Risk Ratio (M‐H, Fixed, 95% CI)	1.05 [0.77, 1.45]
3 Angiographic vasospasm	3	1588	Risk Ratio (M‐H, Random, 95% CI)	0.62 [0.52, 0.72]
4 Unfavorable outcome	3	1976	Risk Ratio (M‐H, Fixed, 95% CI)	0.87 [0.74, 1.02]
5 Hypotension	4	2008	Risk Ratio (M‐H, Fixed, 95% CI)	2.53 [1.77, 3.62]
6 Pneumonia	3	1976	Risk Ratio (M‐H, Fixed, 95% CI)	1.56 [1.23, 1.97]