Table 1.
Comparison of general and disease characteristics of subjects in the two groups.
| Mucus plug group (n = 95) | Control group (n = 56) | P-value | |
|---|---|---|---|
| Age (years) | 6.83 [4.67–9.17] | 6.13 [4.17–9.08] | 0.316 |
| Male | 57 (60.0%) | 31 (55.4%) | 0.573 |
| Urban living | 71 (74.7%) | 44 (78.6%) | 0.593 |
| Birth weight (kg) | 3.30 [3.00–3.50] | 3.25 [3.00–3.60] | 0.997 |
| Premature | 4 (4.4%) | 5 (9.3%) | 0.220 |
| Cesarean | 42 (44.7%) | 31 (57.4%) | 0.136 |
| Neonatal asphyxia | 0 (0.0%) | 1 (1.9%) | – |
| Neonatal oxygen | 1 (1.1%) | 1 (1.9%) | – |
| Feeding mode | 0.174 | ||
| Breastfeeding | 71 (75.5%) | 40 (72.7%) | |
| Formula feeding | 13 (13.8%) | 4 (7.3%) | |
| Mixed feeding | 10 (10.6%) | 11 (20.0%) | |
| Allergy history | 37 (38.9%) | 26 (46.4%) | 0.368 |
| Allergic family history | 39 (41.5%) | 22 (40.0%) | 0.858 |
| Siblings ≥1 | 38 (40.0%) | 20 (35.7%) | 0.601 |
| Asthma hospitalization history | 24 (25.8%) | 8 (14.3%) | 0.097 |
| Systemic glucocorticoid therapy | 13 (14.0%) | 4 (7.3%) | 0.216 |
| Admission season | 0.935 | ||
| Spring | 18 (18.9%) | 11 (19.6%) | |
| Summer | 21 (22.1%) | 10 (17.9%) | |
| Autumn | 41 (43.2%) | 25 (44.6%) | |
| Winter | 15 (15.8%) | 10 (17.9%) | |
| Emergency admission | 51 (53.7%) | 27 (48.2%) | 0.516 |
| PICU treatment | 19 (20.0%) | 7 (12.5%) | 0.238 |
| First asthma diagnoses | 83 (87.4%) | 43 (76.8%) | 0.091 |
| Respiratory infection | 87 (91.6%) | 46 (82.1%) | 0.084 |
| Comorbidity | 49 (51.6%) | 23 (41.1%) | 0.212 |
| Asthma phenotype | 0.614 | ||
| Atopy-only | 47 (59.5%) | 26 (56.5%) | |
| Eos-only | 5 (6.3%) | 1 (2.2%) | |
| T2-high | 15 (19.0%) | 9 (19.6%) | |
| T2-low | 12 (15.2%) | 10 (21.7%) | |
| Severe to critical attacks | 26 (27.4%) | 19 (33.9%) | 0.395 |
| Dyspnea | 50 (52.6%) | 15 (26.8%) | 0.002 |
| Respiratory failure | 13 (13.7%) | 9 (16.1%) | 0.688 |
| Serum total IgE (IU/mL) | 286.85 [119.00–484.90] | 396.00 [248.18–1,265.00] | 0.027 |
| Positive serum allergen detection | 71 (74.7%) | 40 (71.4%) | 0.318 |
| Procalcitonin | 0.15 [0.08–0.46] | 0.22 [0.09–0.53] | 0.758 |
| C-reactive protein | 11.00 [3.35–22.00] | 8.00 [3.43–12.80] | 0.161 |
| White blood cell counts | 9.03 [6.81–11.86] | 8.16 [7.02–11.15] | 0.465 |
| Neutrophil count | 5.49 [3.49–8.24] | 5.40 [3.55–6.83] | 0.460 |
| Eosinophil count | 0.12 [0.01–0.35] | 0.21 [0.02–0.41] | 0.147 |
| Eosinophil % | 1.10 [0.10–4.50] | 2.55 [0.30–4.50] | 0.154 |
The bold values indicated that P < 0.05.