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. 2024 Oct 14;12:1382680. doi: 10.3389/fped.2024.1382680

Table 1.

Comparison of general and disease characteristics of subjects in the two groups.

Mucus plug group (n = 95) Control group (n = 56) P-value
Age (years) 6.83 [4.67–9.17] 6.13 [4.17–9.08] 0.316
Male 57 (60.0%) 31 (55.4%) 0.573
Urban living 71 (74.7%) 44 (78.6%) 0.593
Birth weight (kg) 3.30 [3.00–3.50] 3.25 [3.00–3.60] 0.997
Premature 4 (4.4%) 5 (9.3%) 0.220
Cesarean 42 (44.7%) 31 (57.4%) 0.136
Neonatal asphyxia 0 (0.0%) 1 (1.9%)
Neonatal oxygen 1 (1.1%) 1 (1.9%)
Feeding mode 0.174
 Breastfeeding 71 (75.5%) 40 (72.7%)
 Formula feeding 13 (13.8%) 4 (7.3%)
 Mixed feeding 10 (10.6%) 11 (20.0%)
Allergy history 37 (38.9%) 26 (46.4%) 0.368
Allergic family history 39 (41.5%) 22 (40.0%) 0.858
Siblings ≥1 38 (40.0%) 20 (35.7%) 0.601
Asthma hospitalization history 24 (25.8%) 8 (14.3%) 0.097
Systemic glucocorticoid therapy 13 (14.0%) 4 (7.3%) 0.216
Admission season 0.935
 Spring 18 (18.9%) 11 (19.6%)
 Summer 21 (22.1%) 10 (17.9%)
 Autumn 41 (43.2%) 25 (44.6%)
 Winter 15 (15.8%) 10 (17.9%)
Emergency admission 51 (53.7%) 27 (48.2%) 0.516
PICU treatment 19 (20.0%) 7 (12.5%) 0.238
First asthma diagnoses 83 (87.4%) 43 (76.8%) 0.091
Respiratory infection 87 (91.6%) 46 (82.1%) 0.084
Comorbidity 49 (51.6%) 23 (41.1%) 0.212
Asthma phenotype 0.614
 Atopy-only 47 (59.5%) 26 (56.5%)
 Eos-only 5 (6.3%) 1 (2.2%)
 T2-high 15 (19.0%) 9 (19.6%)
 T2-low 12 (15.2%) 10 (21.7%)
Severe to critical attacks 26 (27.4%) 19 (33.9%) 0.395
Dyspnea 50 (52.6%) 15 (26.8%) 0.002
Respiratory failure 13 (13.7%) 9 (16.1%) 0.688
Serum total IgE (IU/mL) 286.85 [119.00–484.90] 396.00 [248.18–1,265.00] 0.027
Positive serum allergen detection 71 (74.7%) 40 (71.4%) 0.318
Procalcitonin 0.15 [0.08–0.46] 0.22 [0.09–0.53] 0.758
C-reactive protein 11.00 [3.35–22.00] 8.00 [3.43–12.80] 0.161
White blood cell counts 9.03 [6.81–11.86] 8.16 [7.02–11.15] 0.465
Neutrophil count 5.49 [3.49–8.24] 5.40 [3.55–6.83] 0.460
Eosinophil count 0.12 [0.01–0.35] 0.21 [0.02–0.41] 0.147
Eosinophil % 1.10 [0.10–4.50] 2.55 [0.30–4.50] 0.154

The bold values indicated that P < 0.05.