Table 3.

Univariable and multivariable Cox regression analyses for independent predictors of mortality.

Univariate analysis				Multivariate analysis
Parameters	HR	IC 95%	p	HR	IC 95%	p
Male sex	2.682	1.195–6.019	0.017	4.095	1.614–10.386	0.003
Age	0.988	0.958–1.020	0.462
Disease duration	0.990	0.952–1.029	0.610
Digital ulcers	1.052	0.542–2.042	0.881
mRSS	0.989	0.942–1.038	0.658
ATA	1.222	0.588–2.537	0.591
Late NVC pattern	1.607	0.836–3.089	0.55
Significant ILD	2.483	1.161–5.310	0.019	2.407	1.082–5.354	0.031
NYHA class III-IV	2.261	1.261–5.446	0.010	0.735	0.232–2.335	0.602
Pericardial effusion	1.821	0.849–3.908	0.124
TAPSE/sPAP <0.32	2.365	1.230–4.549	0.010	2.439	1.143–5.205	0.021
PVR >5	2.248	1.115–4.533	0.024	1.232	0.500–3.036	0.651
DLCO	0.980	0.958–1.002	0.076
Cardiac Index	0.677	0.166–1.176	0.166
BNP	1.001	1.000–1.003	0.076
Serum urate elevation	1.413	0.743–2.688	0.292

Bold values were statistically significant.