Figure 1.

Immunohistochemical analyzation of Stat3^ΔOHC and Stat3^ΔSC. (A) Stat3 (red) is highly expressed in sensory hair cells (green, Myo7a) or supporting cells in control cochleae, but is reduced in OHC in Stat3^ΔOHC and in supporting cells of the Stat3^ΔSC mice cochleae. (B) However, immunohistochemical analyzation of the cochlear duct indicated no cell loss of OHC (green, Phalloidin), altered innervation (red, βIII-tubulin) or morphology of the sensory epithelium of the cochlea. Ctrl: n = 3, Stat3^ΔSC: n = 3. Scale bars: 20 μm.