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. 2024 Oct 14;17:1455136. doi: 10.3389/fnmol.2024.1455136

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Copyright © 2024 Bieniussa, Stolte, Arampatzi, Engert, Völker, Hagen, Hackenberg and Rak.

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Bulk mRNA sequencing analysis. (A) The mRNA expression volcano plot indicates downregulation when there was a log2fold change of -1 with a significance of p < 0.05. Conversely, upregulation was indicated when there was a log2fold change of 1 with a significance of p < 0.05 compared to control mice. (B) Gene Ontology (GO) and Kyoto Encyclopedia of genes and Genomes (KEGG) term analysis of down- and (C) up-regulated genes performed by Metascape. Ctrl: n = 4, Stat3^ΔOHC: n = 3.