Table 5.
Details of Patients with Local Recurrence (n = 8) in Patients Who Underwent PTR with Curative Intention (n = 40).
| No. | Age/ gender |
NAC | Procedure | LD | Histology | pT (JSCCR) |
pN (JSCCR) |
cM (JSCCR) |
DM | RM | AC | Time to LR |
Recurrent site |
Details |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 56/F | none | LAR+ vagina | LD3 | tub2 | pT3 | pN2 | cM1a (H) | DM0 | RM1 | UFT/UZEL | 11 | central pelvis | vaginal stump |
| 2 | 64/F | none | LAR | LD0 | tub2 | pT3 | pN2 | cM1a (H) | DM0 | RM0 | none | 5 | lateral pelvis | right pelvic wall apart from RM |
| 3 | 74/M | none | APR | LD0 | tub2 | pT2 | pN2 | cM1a (H) | DM0 | RM0 | FOLFOX+ Bmab | 27 | central pelvis | retroperitonium |
| 4 | 50/M | FOLFIRI+ Pmab | APR | LD3 | tub1 | pT3 | pN1 | cM1a (H) | DM0 | RM0 | none | 8 | central pelvis | pelvic floor apart from RM |
| 5 | 59/F | FOLFOX+ Bmab | ISR+ PALN | LD3 | tub2 | pT3 | pN3 | cM1b (PUL, LN) | DM0 | RM0 | none | 2 | central pelvis | pelvic floor apart from RM |
| 6 | 77/F | none | APR+#292 | LD3 | por (PS) | pT3 | pN3 | cM1b (H, LN) | DM1 | RM1 | FOLFOX+ Pmab | 13 | perineal skin | perineal skin |
| 7 | 30/M | FOLFOX+ Pmab | LAR | LD3 | tub2 | pT3 | pN1 | cM1b (H, PUL) | DM0 | RM0 | none | 21 | lateral pelvis | left lateral sacral LN |
| 8 | 50/F | FOLFOX+ Pmab | APR+ uterus | LD0 | tub2 | pT4b (vagina) | pN2 | cM1c2 (H, P, ovary) | DM0 | RM1 | FOLFOX+ Pmab | 2 | central pelvis | retroperitonium |
PTR: primary tumor resection, (N) AC: (neo) adjuvant chemotherapy, LD: lateral dissection, PS: pagetoid spread, JSCCR: Japanese Society for Cancer of the Colon and Rectum, DM: distal margin, RM: radial margin, LR: local recurrence, LN: lymph node