Table 2.
Treatment details of initial radiation therapy and reirradiation courses
| Characteristic | n (%) |
|---|---|
| Initial treatment | |
| PTV volume (cc), median (range) | 207 (11.3-825.5) |
| Prior thoracic radiation therapy | |
| EBRT | 11 (73.3) |
| SBRT | 4 (26.7) |
| Dose of initial thoracic radiation (Gy), median (range) | |
| EBRT | 61.2 (45-96*) |
| SBRT | 50 (50-70) |
| No. of fractions, median (range) | |
| EBRT | 33 (18-43*) |
| SBRT | 5 (5-7) |
| Fractionation schemes of patients treated with initial SBRT (total dose in Gy/fraction) | |
| 50/5 | 3 (75.0) |
| 70/10 | 1 (25.0) |
| BED10 (in Gy) of initial thoracic radiation, median (range) | |
| EBRT | 72.2 (56.3-118.2*) |
| SBRT | 100 (100-119) |
| Interval between thoracic radiation (mo), median (range) | 16.2 (3.6-60.2) |
| Reirradiation | |
| PTV volume (cm3), median (range) | 49.18 (12.2-149.3) |
| Dose fractionation (total dose in Gy/fraction) | |
| 70/10 | 3 (20.0) |
| 65/10 | 4 (26.7) |
| 63/10 | 1 (6.7) |
| 60/10 | 2 (13.3) |
| 50/10 | 5 (33.3) |
| Reirradiation dose, median (range) | 63.0 (50-70) |
| BED10 (in Gy) of 10-fraction regimen, median (range) | 102.7 (75-119) |
Abbreviations: BED = biologically effective dose; EBRT = external beam radiation therapy; PTV = planning target volume; SBRT = stereotactic body radiation therapy.
⁎
A single individual underwent an initial course of conventionally fractionated EBRT to 66 Gy in 33 fractions, with a subsequent course of 30 Gy in 10 fractions at the same site prior to a 10-fraction hypofractionated SBRT course.