Comparison 8. Subgroup analysis for fluoxetine versus TCAs: failure to respond.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 follow‐up <6 weeks	5	341	Odds Ratio (M‐H, Random, 95% CI)	0.67 [0.35, 1.27]
1.1 Fluoxetine vs Amitriptyline	3	207	Odds Ratio (M‐H, Random, 95% CI)	0.56 [0.19, 1.65]
1.2 Fluoxetine vs Clomipramine	1	94	Odds Ratio (M‐H, Random, 95% CI)	0.63 [0.27, 1.45]
1.3 Fluoxetine vs Imipramine	1	40	Odds Ratio (M‐H, Random, 95% CI)	1.42 [0.27, 7.34]
2 follow‐up 6‐16 weeks	18	1742	Odds Ratio (M‐H, Random, 95% CI)	1.02 [0.80, 1.31]
2.1 Fluoxetine vs Amitriptyline	8	570	Odds Ratio (M‐H, Random, 95% CI)	1.06 [0.75, 1.50]
2.2 Fluoxetine vs Desipramine	2	84	Odds Ratio (M‐H, Random, 95% CI)	1.70 [0.56, 5.15]
2.3 Fluoxetine vs Dothiepin/dosulepin	2	144	Odds Ratio (M‐H, Random, 95% CI)	2.13 [1.08, 4.20]
2.4 Fluoxetine vs Doxepine	1	40	Odds Ratio (M‐H, Random, 95% CI)	1.0 [0.28, 3.54]
2.5 Fluoxetine vs Imipramine	4	721	Odds Ratio (M‐H, Random, 95% CI)	0.69 [0.36, 1.34]
2.6 Fluoxetine vs Lofepramine	1	183	Odds Ratio (M‐H, Random, 95% CI)	0.99 [0.55, 1.78]