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. 2013 Jul 17;2013(7):CD004185. doi: 10.1002/14651858.CD004185.pub3

Comparison 11. Subgroup analysis for fluoxetine versus TCAs: failure to complete ‐ inefficacy.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 follow‐up <6 weeks 5 401 Odds Ratio (M‐H, Random, 95% CI) 0.49 [0.16, 1.50]
1.1 Fluoxetine vs Amitriptyline 2 105 Odds Ratio (M‐H, Random, 95% CI) 0.38 [0.07, 2.09]
1.2 Fluoxetine vs Doxepine 1 51 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
1.3 Fluoxetine vs Imipramine 1 40 Odds Ratio (M‐H, Random, 95% CI) 3.15 [0.12, 82.16]
1.4 Fluoxetine vs Nortriptyiline 1 205 Odds Ratio (M‐H, Random, 95% CI) 0.38 [0.07, 2.03]
2 follow‐up 6‐16 weeks 28 2510 Odds Ratio (M‐H, Random, 95% CI) 1.38 [1.02, 1.87]
2.1 Fluoxetine vs Amitriptyline 11 730 Odds Ratio (M‐H, Random, 95% CI) 1.11 [0.50, 2.47]
2.2 Fluoxetine vs Clomipramine 1 120 Odds Ratio (M‐H, Random, 95% CI) 7.37 [0.37, 145.75]
2.3 Fluoxetine vs Desipramine 2 104 Odds Ratio (M‐H, Random, 95% CI) 1.03 [0.20, 5.35]
2.4 Fluoxetine vs Dothiepin/dosulepin 3 271 Odds Ratio (M‐H, Random, 95% CI) 1.34 [0.49, 3.66]
2.5 Fluoxetine vs Doxepine 2 232 Odds Ratio (M‐H, Random, 95% CI) 1.72 [0.60, 4.92]
2.6 Fluoxetine vs Imipramine 9 1053 Odds Ratio (M‐H, Random, 95% CI) 1.40 [0.96, 2.04]