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. 2024 Oct 9;29:101296. doi: 10.1016/j.mtbio.2024.101296

Fig. 8.

Fig. 8

a) The SP-ALN dual-delivery system created by coaxial electrospinning and its application in an implant model with dual-delivery fibers in the tooth socket. Reproduced with permission [118]. Copyright 2021, Elsevier BV. b) Synthesis of hydroxyapatite nanowire@magnesium silicate sheet (HANW@MS) core-shell nanocomposites is detailed. The HANW@MS/CS scaffold significantly promotes bone healing by enhancing rBMSC osteogenesis and angiogenesis. Reproduced with permission [120]. Copyright 2017, American Chemical Society. c) Core-shell nanofibers designed for sequential release of tea polyphenols (TP) and AdipoRon (APR) to manage inflammation and enhance bone healing in periodontitis-related alveolar bone defects. Reproduced with permission [121]. Copyright 2021, American Chemical Society. d) Schematic of DMSNs/SrHA@PGP Scaffold Creation for Dual Delivery of Angiogenic Drugs and Osteogenic Ions, Using 3D Printing and Electrospinning. Reproduced with permission [122]. Copyright 2023, American Chemical Society. e) Biomimetic anti-inflammatory nano-capsules (BANC) with surface cytokine receptors neutralize pro-inflammatory cytokines, easing inflammation. BANC encourages M2 macrophage polarization and inhibits M1 with Resolvin D1 (RvD1) released under NIR light, enhancing femoral bone repair. Reproduced with permission [123]. Copyright 2020, Elsevier BV.