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. 2024 Oct 8;67(20):18170–18193. doi: 10.1021/acs.jmedchem.4c01370

Figure 5.

Figure 5

Correlations between Log D7.4 and (A) the potency of macrocycles 112 to inhibit the growth of L. infantum and (B) kinetic solubilities in phosphate buffered saline at pH 7.4.