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. 2024 Oct 15;121(43):e2405924121. doi: 10.1073/pnas.2405924121

Table 1.

Hazard ratios of all-cause mortality for Models 1 to 3, alongside percentage and number of deaths, according to percentile groups for day light and night light

Light exposure percentile % (N) HR [95%CI] P-value
Model 1 Night 0 to 50% (ref.) 4.09 (1,812)
N = 88,600 50 to 70% 3.88 (688) 1.02 [0.93 to 1.11] 0.69
70 to 90% 4.44 (787) 1.17 [1.08 to 1.28]* 0.00022
90 to 100% 5.01 (444) 1.34 [1.20 to 1.49]* <0.0001
Day 0 to 50% (ref.) 4.35 (1,925)
50 to 70% 4.10 (726) 0.84 [0.77 to 0.92]* 0.00018
70 to 90% 3.96 (701) 0.74 [0.67 to 0.82]* <0.0001
90 to 100% 4.28 (379) 0.66 [0.58 to 0.75]* <0.0001
Model 2 Night 0 to 50% (ref.) 4.06 (1769)
N = 87,052 50 to 70% 3.87 (674) 1.02 [0.93 to 1.11] 0.74
70 to 90% 4.44 (773) 1.18 [1.09 to 1.29]* 0.00012
90 to 100% 4.94 (430) 1.31 [1.18 to 1.46]* <0.0001
Day 0 to 50% (ref.) 4.31 (1,878)
50 to 70% 4.10 (713) 0.86 [0.79 to 0.94]* 0.0011
70 to 90% 3.94 (686) 0.76 [0.69 to 0.84]* <0.0001
90 to 100% 4.24 (369) 0.68 [0.60 to 0.78]* <0.0001
Model 3 Night 0 to 50% (ref.) 4.06 (1,737)
N = 85,562 50 to 70% 3.88 (664) 1.01 [0.92 to 1.10] 0.85
70 to 90% 4.46 (763) 1.15 [1.06 to 1.25]* 0.0015
90 to 100% 4.94 (423) 1.21 [1.08 to 1.35]* 0.00064
Day 0 to 50% (ref.) 4.31 (1,844)
50 to 70% 4.10 (702) 0.90 [0.83 to 0.99]* 0.031
70 to 90% 3.95 (676) 0.84 [0.76 to 0.93]* 0.00075
90 to 100% 4.27 (365) 0.83 [0.72 to 0.94]* 0.0042

Hazard ratios represent risks of all-cause mortality across light exposure percentile groups, compared to a reference light exposure group, for day and night light. Model 1 was adjusted for age, sex, ethnicity, and photoperiod; Model 2 was additionally adjusted for employment status, education, income, and deprivation; Model 3 was further adjusted for physical activity, smoking status, alcohol consumption, urbanicity, and social activity.

*P < 0.05.