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. 2024 Oct 15;121(43):e2405924121. doi: 10.1073/pnas.2405924121

Table 2.

Hazard ratios of cause-specific mortality for Models 1 to 3, alongside percentage and number of deaths, according to percentile groups for day light and night light

Cardiometabolic mortality Other-cause mortality
Light exposure percentile % (N) HR [95%CI] P-value % (N) HR [95%CI] P-value
Model 1 Night 0 to 50% (ref.) 0.84 (373) 3.22 (1,426)
50 to 70% 0.85 (150) 1.08 [0.89 to 1.31] 0.22 3.01 (534) 1.00 [0.91 to 1.11] 0.48
70 to 90% 0.97 (172) 1.25 [1.04 to 1.49]* 0.0091 3.43 (608) 1.15 [1.04 to 1.26]* 0.0025
90 to 100% 1.12 (99) 1.46 [1.16 to 1.82]* 0.00051 3.86 (342) 1.30 [1.15 to 1.47]* <0.0001
Day 0 to 50% (ref.) 0.93 (411) 3.38 (1,497)
50 to 70% 0.82 (146) 0.79 [0.65 to 0.96]* 0.0099 3.23 (573) 0.86 [0.78 to 0.95]* 0.0015
70 to 90% 0.90 (159) 0.77 [0.62 to 0.95]* 0.0084 3.05 (541) 0.74 [0.66 to 0.83]* <0.0001
90 to 100% 0.88 (78) 0.61 [0.46 to 0.80]* 0.00027 3.38 (299) 0.68 [0.59 to 0.79]* <0.0001
Model 2 Night 0 to 50% (ref.) 0.84 (365) 3.20 (1,391)
50 to 70% 0.86 (150) 1.10 [0.90 to 1.33] 0.17 2.99 (520) 0.99 [0.90 to 1.10] 0.45
70 to 90% 0.97 (169) 1.26 [1.05 to 1.52]* 0.0068 3.43 (597) 1.15 [1.05 to 1.27]* 0.0019
90 to 100% 1.11 (97) 1.45 [1.16 to 1.83]* 0.00064 3.79 (330) 1.27 [1.13 to 1.44]* <0.0001
Day 0 to 50% (ref.) 0.92 (402) 3.35 (1,459)
50 to 70% 0.83 (145) 0.81 [0.66 to 0.99]* 0.018 3.22 (561) 0.88 [0.79 to 0.97]* 0.0058
70 to 90% 0.91 (159) 0.80 [0.64 to 0.99]* 0.019 3.02 (526) 0.76 [0.68 to 0.85]* <0.0001
90 to 100% 0.86 (75) 0.61 [0.46 to 0.82]* 0.00044 3.35 (292) 0.72 [0.62 to 0.83]* <0.0001
Model 3 Night 0 to 50% (ref.) 0.84 (360) 3.19 (1,364)
50 to 70% 0.86 (148) 1.09 [0.90 to 1.32] 0.2 2.99 (512) 0.99 [0.89 to 1.09] 0.41
70 to 90% 0.97 (166) 1.22 [1.01 to 1.47]* 0.019 3.45 (590) 1.13 [1.02 to 1.24]* 0.0091
90 to 100% 1.12 (96) 1.33 [1.06 to 1.68]* 0.0069 3.79 (324) 1.17 [1.03 to 1.32]* 0.0064
Day 0 to 50% (ref.) 0.93 (397) 3.34 (1,430)
50 to 70% 0.82 (141) 0.84 [0.69 to 1.03] 0.051 3.24 (554) 0.92 [0.83 to 1.02] 0.064
70 to 90% 0.92 (158) 0.91 [0.73 to 1.12] 0.19 3.02 (517) 0.84 [0.75 to 0.94]* 0.0011
90 to 100% 0.86 (74) 0.76 [0.56 to 1.02]* 0.033 3.38 (289) 0.86 [0.74 to 0.99]* 0.02

Hazard ratios represent risks of cardiometabolic and other-cause mortality across light exposure percentile groups, compared to a reference light exposure group, for day and night light. Model 1 was adjusted for age, sex, ethnicity, and photoperiod; Model 2 was additionally adjusted for employment status, education, income, and deprivation; Model 3 was further adjusted for physical activity, smoking status, alcohol consumption, urbanicity, and social activity.

*P < 0.05.