FIGURE 3.

Sequence logos of main subfolds of alpha‐solenoid proteins. One representative Pfam family per each subfold is considered. The sequence logos were made by the Skylign tool (Wheeler et al., 2014) with default parameters using seed Pfam alignment as an input. Occupancy is the probability of observing a letter at position k, and every amino acid has a unique color by default parameters. The length of the sequence logos is modified to fit into one repeat unit length of the specific Pfam superfamily. ANK, ankyrin repeats; ARM, armadillo repeats; HEAT, Huntingtin; Sel1, Sel‐1‐like repeats; PPR, pentatricopeptide repeats; PUF, Pumilio repeats; TAL, transcription activator‐like; TPR, tetratricopeptide repeats.