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. 2019 Jun 26;171(1):1–12. doi: 10.1093/toxsci/kfz146

Figure 2.

Figure 2.

Fenofibrate attenuated TP-induced liver injury. A, Hematoxylin and eosin staining of liver. Solid arrow: congestion. B, Serum AST, ALT, and ALP enzymes activity. C, qPCR analysis of inflammatory factor mRNAs in liver. D, Fenofibrate recovered the increased serum medium- and long-chain acylcarnitine levels. E, qPCR analysis was performed to measure the expression of peroxisome proliferator-activated receptor α target gene mRNAs. Serum AST and ALT activity in Ppara+/+ mice (F) and Ppara−/− mice (G). Serum medium- and long-chain acylcarnitine levels in Ppara+/+ mice (H) and Ppara−/− mice (I). All data were expressed as mean ± SEM (n = 5). *p < .05, **p < .01, and ***p < .001.