Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Long-chain acylcarnitines developed defense response by activating NRF2 and NOTCH signaling. qPCR analysis of the gene expression of NRF2 (A) and NOTCH (B) pathway in WT mice. C, Western blot was used to measure NRF2 and NOTCH3 in WT mice. qPCR analysis of the Nrf2 (and NRF target genes) (D) and Notch (and NOTCH target genes) (E) mRNAs in primary hepatocytes after treatment with 150 µM 18:0-carnitine. All data were expressed as mean ± SEM. *p < .05, **p < .01, and ***p < .001.
