Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Oct 27;14:25610. doi: 10.1038/s41598-024-76992-9

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — Systemic lipid profiles after HFD-induced hypercholesterolemia in Ldlr^−/− mice. Plasma concentrations of (A) triglycerides (mg/dL), (B) total cholesterol (mg/dL), (C) LDL cholesterol (low-density lipoprotein—mg/dL), and (D) FFA (Free fatty acids—µM—micromolar) in male and female mice with deletion of the low-density lipoprotein (LDL) receptor (Ldlr^−/−) and age- and sex-matched wild-type (WT) control before (baseline) and 10 days after being exposed to a low-fat diet (LFD) or high-fat diet (HFD), which corresponds to the time point when the rib resection surgeries were performed (0 dpr). The dashed lines represent the overall mean value of the group of WT mice under LFD at baseline and were used as a reference in each graph for comparison with all other groups. Data are displayed as the mean ± SD (n = 4 in each group). Statistical analysis was performed using two-way analysis of variance (ANOVA) followed by Fisher’s LSD test. Significant differences between groups are expressed as *p < 0.05. dpr = days post-resection.