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Change in the laser-induced choroidal neovascularization (CNV) area after intravitreal treatment (IVT) or subconjunctival treatment (subconj.) with apatinib and bevacizumab in mice with laser-induced CNV. Laser setting (300 mW, 100 ms, 95% white bubble, 78 D lens). CNV was stained using Alexa Fluor 594-conjugated isolectin B4 (1:100 dilution). Data were analyzed using the Mann–Whitney U test (**p < 0.01 vs. only laser-induced CNV) and are expressed as the mean ± S.E. (n = 6–17).
