Fig. 2. Heterologous expression of the aqu biosynthetic gene cluster in A. nidulans. (A) The aqu BGC in A. gemini is depicted. Gene names from the aqu cluster are indicated, as well as the backbone gene domain organisation. (B) LC-DAD (254 nm) chromatograms of A. nidulans cultures expressing different combinations of the aqu genes leading to the production of 1a, 1b, 2a and 2b as well as 5 (Fig. 1), as well as A. gemini MST-FP2131 grown on jasmine rice.
