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. 2024 Oct 28;14(46):34253–34260. doi: 10.1039/d4ra05917d

Partition coefficients (K) and extraction efficiency (EE%) for the {DES [ChCl : sugar] + K3PO4 + H2O} system at 298.15 Ka.

Molar ratio 2 : 1 Overall composition/wt% K EE%
[DES] [K3PO4]
Ibuprofen
ChCl/fructose 41.35 30.90 2.50 71.43
39.91 30.90 2.33 69.97
38.43 30.90 2.18 68.55
37.00 30.90 1.99 66.56
35.56 30.90 1.72 63.24
ChCl/glucose 41.35 30.90 2.62 72.38
39.91 30.90 2.45 71.01
38.43 30.90 2.30 69.70
37.00 30.90 2.11 67.85
35.56 30.90 1.84 64.79
Acetaminophen
ChCl/fructose 41.35 30.90 3.51 77.83
39.91 30.90 3.34 76.96
38.43 30.90 3.19 76.13
37.00 30.90 3.01 75.06
35.56 30.90 2.73 73.19
ChCl/glucose 41.35 30.90 3.62 78.35
39.91 30.90 3.45 77.53
38.43 30.90 3.30 76.74
37.00 30.90 3.12 75.73
35.56 30.90 2.84 73.96
Aspirin
ChCl/fructose 41.35 30.90 5.69 85.05
39.91 30.90 5.52 84.66
38.43 30.90 5.37 84.30
37.00 30.90 5.19 83.84
35.56 30.90 4.91 83.08
ChCl/glucose 41.35 30.90 5.87 85.44
39.91 30.90 5.70 85.07
38.43 30.90 5.55 84.73
37.00 30.90 5.37 84.30
35.56 30.90 5.09 83.58
a

The partitioning coefficient, temperature, and pressure standard uncertainties (σ) are as follows: u(K) = 0.15, u(T) = 0.05 K and u(p) = 0.5 kPa, respectively.