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. Author manuscript; available in PMC: 2024 Oct 28.
Published in final edited form as: Structure. 2019 Apr 18;27(6):1029–1033.e3. doi: 10.1016/j.str.2019.03.015

Figure 3. Structural Similarity of the MORC3-CW Complexes.

Figure 3.

(A) Structural overlay of the MORC3-CW in complex with NS1 peptide (yellow) and H3K4me3 peptide (pink) (PDB: 5SVX).

(B) The fold change in H3N2 influenza virus infectivity in a single round of infection in mCherry-MORC3-positive cells compared with mCherry-negative cells from the same sample. Infectivity measured as a percentage of cells positive of expression of the viral NP protein. The results presented are representative of two independent experiments. The experiments were carried out in triplicate (in duplicate for the D67A mutant). Data are represented as means ± SEM. The statistical significance was determined using the unpaired t test, *p < 0.05.

See also Figures S3 and S4.