Table 3.
Phage-resistance systems beyond CRISPR-Cas and R/M identified by PADLOC. Bold face text indicates the systems selected for functional evaluation
| Strain | PADLOC identified phage-resistance systems | ORF number | Location on genome |
|---|---|---|---|
| ST1A | AbiD | 1639 | 1601461–1602441c |
| PD-T4-6 | 1341 | 1312938–1314809c | |
| PDC-S29 | 1815 | 1760204–1760938c | |
| UCCSt95 | PDC-S07 | 0654 | 642989–643378 |
| PD-T4-6 | 1285 | 1259864–1261735c | |
| CNRZ302 | AbiD | 03920 | 760545–761435 |
| PD-T4-6 | 1370 | 1309158–1311029c | |
| CNRZ385 | GAO_19 (SIR2, HerA) | 0755, 0756 | 691015–693872 |
| PD-T4-6 | 1417 | 1319589–1321460c | |
| CNRZ760 | AbiD | 0656 | 641609–642619 |
| PD-T4-6 | 1366 | 1312221–1314092c | |
| CNRZ887 | AbiEi/Eii | 1349, 1350 | 1311759–1312675 |
| PD-T4-6 | 1277 | 1239802–1241673c | |
| CNRZ1151 | AbiEi/Eii | 1395, 1396 | 1334306–1335222 |
| PD-T4-6 | 1328 | 1271059–1272930c | |
| 90728 | AbiD | 0633 | 621588–622598 |
| PD-T4-6 | 1371 | 1323778–1325649c | |
| 90729 | AbiD | 0642 | 633131–634141 |
| PD-T4-6 | 1342 | 1313302–1315173c | |
| Dodola (dolA, dolB) | 1798, 1799 | 1746878–1748836c | |
| 90730 | AbiEi/Eii | 1386, 1387 | 1336150–1337066 |
| Kiwa (kwaB, kwaA) | 0688, 0689 | 673224–674776 | |
| PD-T4-6 | 1310 | 1262508–1264379c | |
| STR1 | GAO_19 (SIR2,HerA) | 0691, 0692 | 681184–684217 |
| PD-T4-6 | 1358 | 1311954–1313825c | |
| ST19 | Hachiman type I | 0447, 0448 | 453847–457022 |
| PD-T4-6 | 1322 | 1295405–1297276c | |
| ST55 | AbiD | 0646 | 624941–625951 |
| PDC-S58 | 0671 | 651314–652729 | |
| GAO_19 (SIR2, HerA) | 0721, 0722 | 698303–701093 | |
| PDC-S06 | 0741 | 716435–718624 | |
| PDC-S61 | 0744 | 720509–721261 | |
| PD-T4-6 | 1380 | 1327282–1329153c | |
| ST128 | PD-T4-6 | 1338 | 1305964–1307835 |
| 4021 | GAO_19 (SIR2, HerA) | 0687, 0688 | 681458–684306 |
| AbiD | 1632 | 1594135–1595115 c | |
| PD-T4-6 | 1335 | 1305732–1307603c | |
| 4052 | PDC-S07 | 0664 | 643370–643759 |
| PD-T4-6 | 1298 | 1239930–1241801c | |
| AbiEi/Eii | 1371, 1372 | 1309955–1310871 | |
| 4078 | AbiD | 0760 | 741877–742767 |
| PD-T4-6 | 1344 | 1286907–1288778c | |
| 4134 | PD-T4-6 | 1337 | 1300554–1302425c |
| 4145 | Gabija (gajA, gajB) | 0685, 0686 | 679404–682765 |
| GAO_19 (SIR2/HerA) | 0663, 0664 | 657103–659392 | |
| PD-T4-6 | 1313 | 1283833–1285704c | |
| 4147 | AbiEi/Eii | 1393, 1394 | 1337577–1338493 |
| PD-T4-6 | 1317 | 1263929–1265800c | |
| MM1 | PD-T4-6 | 1333 | 1295884–1297755c |
| MM20 | PD-T4-6 | 0620 | 604802–606673 |
| Sofic | 0248 | 248143–248967 | |
| Sofic | 1073 | 1051268–1052092c | |
| AVA116 | PD-T4-6 | 1250 | 1210550–1212421c |
| AVA1121 | PD-T4-6 | 1339 | 1276199–1278070c |