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. 2024 Oct 28;30:190. doi: 10.1186/s10020-024-00946-0

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Protein expression levels of PRDM family members in uterine corpus endometrial carcinoma (UCEC) and normal endometrial tissue. A Protein levels of PRDM family members in uterine corpus endometrial carcinoma (UCEC) patients were analyzed using data from UALCAN. The results indicate significant differences in protein levels among the family members. Statistical significance was observed for p < 0.01 and *p < 0.001, while no significant difference (NS) was found in some cases. B MECOM, PRDM5, PRDM10, and PRDM11 expression patterns in UCEC and normal endometrial tissue were investigated using immunohistochemistry images in the HPA database. The images demonstrate these proteins' distinct localization and expression patterns in different tissues. PRDM5 exhibits a significantly higher H-score in cancer tissues compared to normal tissues. In contrast, PRDM12 is undetectable in normal tissues but presents a low H-score in cancer tissues