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. 2024 Oct 15;16(10):4064–4079. doi: 10.4251/wjgo.v16.i10.4064

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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Mechanisms of immune evasion in colorectal cancer by cancer stem cells. CSC: Cancer stem cell; TME: Tumor microenvironment; TCR: T cell receptor; MHC: Major histocompatibility complex; MDSC: Myeloid-derived suppressor cell; PD-L1: Programmed cell death ligand 1; PD-1: Programmed cell death protein 1; STAT 3: Signal transducer and activator of transcription 3; AP-1: Activating protein-1; HLA: Human leukocyte antigen; IFNAR1: Interferon alpha/beta receptor 1; Treg: Regulatory T cell; IL: Interleukin; TGF: Transforming growth factor.