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. 2024 Oct 15;16(10):4194–4208. doi: 10.4251/wjgo.v16.i10.4194

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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Overexpression of steroid receptor RNA activator 1 suppresses esophageal squamous cell carcinoma cell proliferation and glycolysis in vitro. A: Steroid receptor RNA activator 1 (SRA1) overexpression was verified by quantitative reverse transcription-polymerase chain reaction; B: Overexpression of SRA1 caused an obvious decrease in proliferation rate in EC9706 and TE1 cells; C: Upregulation of SRA1 triggered a decrease of GLUT1 and LDHA in EC9706 and TE1 cells. ^aP < 0.01 vs negative control; NC: Negative control; SRA1: Steroid receptor RNA activator 1.