Figure 1.

The workflow of eRNA-IDO

eRNA-IDO comprises two functional modules: eRNA-ID for eRNA identification and eRNA-Anno for interactome discovery and functional annotation. eRNA, enhancer RNA; PCG, protein-coding gene; SEdb, super-enhancer database; FANTOM5, functional annotation of the mammalian genome 5; ENCODE, ENCyclopedia of DNA Elements; SCREEN, Search Candidate cis-Regulatory Elements by ENCODE; RNAPII, RNA polymerase II; KEGG, Kyoto Encyclopedia of Genes and Genomes; MSigDB, Molecular Signatures Database; RBP, RNA-binding protein; TSS, transcription start site; TF, transcription factor; BED, browser extensible data; GTF, gene transfer format; CPC2, Coding Potential Calculator 2.