Table 1.
Description of the studied PDAC cases according to clinicopathological parameters (n = 98)
| No. | % | ||
|---|---|---|---|
| Gender | Male | 70 | 71.4 |
| Female | 28 | 28.6 | |
| Virology (HCV infection) | Negative | 76 | 77.6 |
| Positive | 22 | 22.4 | |
| CA19.9 (n = 50) | Low (< 175) | 25 | 50.0 |
| High (≥ 175) | 25 | 50.0 | |
| Direct bilirubin (n = 90) | < 6 | 45 | 50.0 |
| ≥ 6 | 45 | 50.0 | |
| Tumor recurrence (n = 38) | Absent | 20 | 52.6 |
| Present | 18 | 47.4 | |
| Necrosis | Absent | 81 | 82.7 |
| Present | 17 | 17.3 | |
|
Epithelial Desmoplasia predominance |
Desmoplasia | 53 | 54.1 |
| Epithelial | 38 | 38.8 | |
| Equal | 7 | 7.1 | |
| TIMCs | < 10 | 39 | 44.3 |
| ≥ 10 | 49 | 55.7 | |
| Tumor Size (n = 97) | ≤ 5 | 83 | 85.6 |
| > 5 | 14 | 14.4 | |
| Histologic grade | I | 11 | 11.2 |
| II | 78 | 79.6 | |
| III | 9 | 9.2 | |
| Low | 88 | 89.8 | |
| High | 10 | 10.2 | |
| LVI | Absent | 64 | 65.3 |
| Present | 34 | 34.7 | |
| Perineural invasion | Absent | 2 | 2.0 |
| Present | 96 | 98.0 | |
| Resection margin | Free | 67 | 68.4 |
| Involved | 31 | 31.6 | |
| N stage | N0 | 23 | 23.5 |
| N1 | 44 | 44.9 | |
| N2 | 31 | 31.6 | |
| LN status | Negative | 23 | 23.5 |
| Positive | 75 | 76.5 | |
| T stage | T1 | 3 | 3.1 |
| T2 | 56 | 57.1 | |
| T3 | 39 | 39.8 | |
| Stage grouping | Early | 59 | 60.2 |
| Advanced | 39 | 39.8 | |
- CA19-9: Carbohydrate antigen 19 − 9 -HCV: Hepatitis C virus
- TIMCs: Tumor-infiltrating mononuclear cells - LVI: Lymphovascular invasion
-LN: Lymph node - T: Tumor stage