Fig. 3.

The role of stimuli-responsive hydrogels in gastrointestinal cancer therapy. Currently, most of the studies have focused on the application of pH- and thermo-sensitive hydrogels in GI cancer therapy. However, other kinds of hydrogels including redox- and enzyme-responsive are also present that future studies can focus on their application in GI tumor therapy. Such stimuli-sensitive hydrogels can release the cargo (drug or gene) at the tumor site to improve their internalization in reducing tumorigenesis. (Created by Biorender.com)